Take the New York metropolitan area’s progress against the coronavirus out of the equation and the numbers show the rest of the U.S. is moving in the wrong direction, with the known infection rate rising even as states move to lift their lockdowns, an Associated Press analysis found Tuesday.

New confirmed infections per day in the U.S. exceed 20,000, and deaths per day are well over 1,000, according to figures from Johns Hopkins University. And public health officials warn that the failure to flatten the curve and drive down the infection rate in places could lead to many more deaths — perhaps tens of thousands — as people are allowed to venture out and businesses reopen.

“Make no mistakes: This virus is still circulating in our community, perhaps even more now than in previous weeks” said Linda Ochs, director of the Health Department in Shawnee County, Kansas.

Elsewhere around the world, Britain’s official coronavirus death toll, at more than 29,000, topped that of Italy to become the highest in Europe and second-highest in the world behind the United States. The official number of dead worldwide surpassed a quarter-million, by Johns Hopkins’ count, though the true toll is believed to be much higher.

The New York metropolitan area, consisting of about 20 million people across a region that encompasses the city’s northern suburbs, Long Island and northern New Jersey, has been the hardest-hit corner of the country, accounting for at least one-third of the nation’s 70,000 deaths. People across the densely packed region live practically on top of each other in apartment buildings and ride together on subways, buses and trains.

When the still locked-down metropolitan area is included, new infections in the U.S. appear to be declining, according to the AP analysis. It found that the five-day rolling average for new cases has decreased from 9.3 per 100,000 people three weeks ago on April 13 to 8.6 on Monday.

But subtracting the New York area from the analysis changes the story. Without it, the rate of new cases in the U.S. increased over the same period from 6.2 per 100,000 people to 7.5.

While the daily number of new deaths in the metro area has declined markedly in recent weeks, it has essentially plateaued in the rest of the U.S., the analysis found. Without greater New York, the rolling five-day average for new deaths per 500,000 people dropped slightly from 1.86 on April 20th to 1.82 on Monday.

U.S. testing for the virus has been expanded, and that has probably contributed to the increasing rate of confirmed infections. But it doesn’t explain the entire increase, said Dr. Zuo-Feng Zhang, a public health researcher at the University of California at Los Angeles.

“This increase is not because of testing. It’s a real increase,” he said.

Pockets of America far from New York City are seeing ominous trends.

Deaths in Iowa surged to a new daily high of 19 on Tuesday, and 730 workers at a single Tyson Foods pork plant tested positive. On Monday, Shawnee County, home to Topeka, Kansas, reported a doubling of cases from last week on the same day that business restrictions began to ease.

Gallup, New Mexico, is under a strict lockdown until Thursday because of an outbreak, with guarded roadblocks to prevent travel in and out of the city and a ban on more than two people in a vehicle. Authorities have deployed water tankers, hospital space is running short, and a high school gym is now a recuperation center with 60 oxygen-supplied beds.

On Monday, a model from the University of Washington nearly doubled its projection of deaths in the U.S. from the coronavirus to around 134,000 through early August, with a range of 95,000 to nearly 243,000.

Dr. Christopher Murray, director of the institute that created the projections, said the increase is largely because most states are expected to ease restrictions by next week.

Without stay-at-home orders and similar measures, Murray said, “we would have had exponential growth, much larger epidemics and deaths in staggering numbers.” But cooperation is waning, with cellphone location data showing people are getting out more, even before their states reopen, he said.

President Donald Trump, asked about the projections before traveling to Arizona to visit a mask factory, disputed the accuracy of models in general and said keeping the economy closed carries deadly costs of its own, such as drug abuse and suicide.

“We have to get our country open,” Trump said.

Zhang said it worries him that the rate of new cases is increasing at the same time some states are easing up: “We’re one country. If we’re not moving in the same step, we’re going to have a problem.”

He said he is particularly concerned about Florida and Texas, places where cases have been rising steadily and the potential for explosions seems high.